Citrulline: Benefits, How to Use It, and the Difference Between Citrulline and Creatine
If you train regularly, you have likely heard of Citrulline, especially if you are looking for a supplement to help with your pump and workout performance.
But is Citrulline just an ingredient found in pre-workout supplements? Is it better than creatine? And can you use both together?
In this article from Muscle Hub, we will learn about Citrulline, how it works, its benefits, the difference between it and creatine, and how to choose the right supplement for your goal.
What is Citrulline?
Citrulline, or L-Citrulline, is a non-essential amino acid involved in several processes within the body.
One of its most important roles is its link to the Nitric Oxide production pathway, which plays a role in vasodilation and blood flow.
For this reason, Citrulline has become a common ingredient in pre-workout supplements, especially among those interested in the pump and performance during training.
If you are looking for Citrulline specifically for this use, you can check out Rule One Citrulline 198g – 60 Servings, which provides 3 grams of L-Citrulline per serving according to product data.
What are the benefits of Citrulline?
1. Supporting Blood Flow
One of the main reasons for using Citrulline in sports supplements is its role in supporting the nitric oxide pathway.
Increasing the availability of L-Arginine in the body can support nitric oxide production, which is linked to vasodilation and blood flow.
This is one of the reasons why Citrulline is a common ingredient in pre-workout supplements.
2. Supporting Muscle Pump
If your primary goal during training is to get a better pump, then Citrulline is one of the ingredients used for this purpose.
The pump is the feeling of muscle fullness during training resulting from increased blood flow to the muscles; however, it remains a temporary effect and does not necessarily mean you are building more muscle.
Therefore, if the pump is an important part of your training experience, you can check out the Rule One Citrulline formula as one of the available options at Muscle Hub.
3. Supporting Workout Performance
Citrulline may help with some aspects of workout performance, especially in activities that require high-intensity effort or multiple sets.
However, the effect varies depending on the person, type of training, and dosage used, so Citrulline should not be viewed as a magic solution for increasing performance.
L-Citrulline or Citrulline Malate?
When looking for Citrulline, you will often find two common forms:
L-Citrulline
Which is Citrulline in its direct form.
Citrulline Malate
A compound that combines Citrulline with Malic Acid.
The difference is important when comparing products because the weight of the product or the dosage written on the front does not necessarily mean the entire amount is L-Citrulline.
Therefore, always read the Supplement Facts to know the actual amount of Citrulline in the serving.
When should you use Citrulline?
Citrulline is usually used before a workout, as part of your supplement regimen around the training session.
For example, the Rule One Citrulline data on Muscle Hub recommends taking a serving 20–30 minutes before training.
However, timing and dosage vary from product to product, so follow the instructions on the product you are using.
Citrulline and Creatine: What is the difference?
Here comes the most common question:
Should I use Citrulline or Creatine?
The answer is simple: the two are not substitutes for each other.
Creatine and Citrulline work in different ways, and therefore each can have a different place in your supplement regimen.
|
|
Citrulline |
Creatine |
|
Primary Use |
Supporting blood flow and pump |
Supporting energy production and performance |
|
Common Use |
Pre-workout |
Daily |
|
Pump |
One of its most famous uses |
Not the primary goal |
|
High-Intensity Performance |
May support some aspects of performance |
One of the most studied uses |
|
Muscle Mass Gain |
Potential indirect effect |
Helps with regular training |
|
Can they be combined? |
Yes |
Yes |
How does Creatine work?
Creatine is a substance that occurs naturally in the body, and a large portion of it is stored in the muscles.
When performing high-intensity activity, the Phosphocreatine system helps regenerate ATP, which is a rapid source of energy used by the muscles.
For this reason, Creatine Monohydrate has become one of the most famous and well-studied sports supplements.
Options available on Muscle Hub include Nutrex Creatine Monohydrate 300g, which provides 5 grams of creatine monohydrate per serving according to product data.
Also available is Crea Power Creatine 400g, which contains 5 grams of Creatine Monohydrate per scoop according to product data.
Is Creatine better than Citrulline?
It is more accurate not to compare them by considering one "better" in an absolute sense.
If your goal is to support strength and performance in high-intensity workouts, Creatine has a clear and distinct role.
If your main concern is the pump and blood flow during training, Citrulline is used for that purpose.
Therefore, the choice depends on your goal for the supplement and not just the name of the supplement.
Can Citrulline and Creatine be used together?
Yes, you can use both together.
The reason is that each supplement has a different function.
You can use Creatine daily, while using Citrulline as part of your pre-workout regimen.
In some cases, you may find both already present within the same pre-workout formula.
For example, Applied Nutrition ABE Pre-Workout contains, according to product data, 4 grams of Citrulline Malate and 3.25 grams of Creatine Monohydrate per serving, in addition to other ingredients like caffeine and beta-alanine.
This highlights the importance of reading Supplement Facts before adding separate supplements, so you know exactly how much of each ingredient you are getting.
Does Citrulline build muscle?
Citrulline is not a muscle-building supplement directly.
It may help support workout performance for some, but muscle building depends primarily on:
- Resistance training
- Appropriate nutrition
- Getting enough protein
- Appropriate calorie intake for your goal
- Sleep and recovery
- Consistency
Therefore, Citrulline can be part of a supplement regimen, but it is not a substitute for the basics.
Does Creatine cause weight gain?
Some people may notice an increase in body weight after starting to use Creatine.
This increase might be related to increased water inside the muscles, especially at the beginning of use, and not necessarily an increase in fat.
Therefore, a rapid weight gain after starting Creatine should not automatically be interpreted as an increase in fat.
Which to choose: Citrulline or Creatine?
Instead of searching for the "best supplement," first define your goal.
If your goal is to support strength and performance
Creatine Monohydrate can be a primary option in your supplement regimen, especially with regular training.
You can check out the Creatine collection on Muscle Hub and compare the available options.
If your goal is the pump
Citrulline can be suitable for this purpose, especially before a workout.
Available options include Rule One Citrulline.
If you want to combine both
You can use Citrulline and Creatine together, or choose a pre-workout that already contains both, such as Applied Nutrition ABE Pre-Workout.
Conclusion
Citrulline and Creatine are among the most famous sports supplements, but they are not substitutes for each other.
Citrulline is more associated with supporting nitric oxide production and blood flow, which is why it is used often before training and by those concerned with the pump.
As for Creatine, it is mainly associated with the muscle energy system and supporting performance in high-intensity workouts.
Consequently, there is no reason to choose only one just because it is "better."
Define your goal first, then choose the supplement that fits that goal.
And more importantly than any supplement: good training, appropriate nutrition, enough protein, sleep, and consistency.
FAQs about Citrulline and Creatine
Is Citrulline taken before a workout?
Yes, Citrulline is usually used before a workout. Always follow the dosage and timing instructions on the product.
Can Citrulline be taken with Creatine?
Yes, they can be combined because each has a different function.
Does Citrulline increase the pump?
It can help support blood flow and nitric oxide production, which is one of the reasons it is popular in pre-workout supplements.
Is Citrulline better than Creatine?
No, because they do not perform the same function. Creatine focuses more on the energy system and high-intensity performance, while Citrulline is more related to blood flow and the pump.
Is Citrulline Malate the same as L-Citrulline?
No. Citrulline Malate combines Citrulline and Malic Acid, while L-Citrulline is Citrulline in its direct form.
Can Creatine and Citrulline be used together?
Yes, and you may find them together in some pre-workout formulas. Therefore, it is important to read the Supplement Facts to know the total amount you are getting of each ingredient.